Clearing more than four matches will still result in four pieces instead of more. In a 2-Player game, if multiple capsule matches are made in a single move, colored pieces will fall into the opponent's bottle depending on the colors cleared which is determined by what the colors of the matched rows or columns are, and also the amount of matches made during the move, where clearing two, three, or four lines will result in two, three, or four pieces falling into the opponent's bottle. Because of this, the cooldown between a capsule landing and a new capsule being added is shorter than in 1-Player game. In 2-Player game, the vitamin capsules appear at the mouth of the bottle instead of being thrown in. He will throw that capsule if the current capsule landed, and will repeat until all the viruses are eliminated or a game over is obtained. Mario throws vitamin capsules into the bottle and will have another ready, which acts as a preview on what the next vitamin capsule is. For the Game Boy version, these patterns correspond to black, white, and gray/textured colors.
They come in six different color combinations that include red, blue, or yellow (all red, all blue, all yellow, red and blue, yellow and blue, and red and yellow). counterpart, capsules were introduced, where they were known as vitamin capsules.
